(The Center Square) – The U.S. Drug Enforcement Administration released its latest report on drug threats, highlighting progress in the fight against fentanyl, a powerful opioid responsible for most overdose deaths.
Even so, fentanyl remains at the top of the DEA threat assessment.
“Mexican cartels’ production, trafficking, and distribution of powerful illicit synthetic drugs, chiefly fentanyl and methamphetamine, represent a dire threat to public health, the rule of law, and national security in the United States,” the report said. “The Sinaloa and Jalisco New Generation Cartels (CJNG), together with their procurement, distribution, and financial support networks stretching across Latin America, China, and other key global nodes, remain the dominant threats for the trafficking of these and other drugs into the United States.”
The move away from plant-based drugs to synthetics has helped the cartels rake in ever-more cash. Cartels maintain steady supply chains for precursor chemicals, primarily from China and India, needed to produce these synthetic drugs.
In the 12 months ending in October 2024, the United States recorded 52,385 overdose deaths from synthetic opioids – a 33% decline – while overall overdose deaths, from any drug, declined about 26%, according to the most recent available CDC provisional data. Provisional data from the CDC showed that 74,702 of the 107,543 total drug overdose deaths in 2023 involved synthetic opioids, primarily fentanyl. That’s about 69% of all overdose deaths in the U.S.
The DEA seized about 29% less fentanyl in 2024 compared to the prior year. In 2024, DEA seized 21,936 pounds of fentanyl. The agency also seized 61.1 million fake pills in 2024, a 24% decrease from the previous year. Data from the El Paso Intelligence Center’s National Seizure System – which consolidates drug seizure data from federal, state, and local agencies throughout the United States – indicated a similar trend, with 23,256 total kilograms seized in 2024, down from the previous year.
Fentanyl purity also fell last year, according to DEA testing. In 2024, the average fentanyl pill contained 1.94 milligrams of fentanyl, ranging from a low of 1.58 mg to a high of 2.18 mg. Based on these analyses, DEA forensic laboratory results found that about 5 out of 10 fake pills contain 2mg or more of fentanyl. The average purity of fentanyl powder samples was 11.36%, ranging from exhibits that contained almost no fentanyl (0.07%) to 82% purity.
“Fentanyl purity declined throughout 2024, consistent with indicators that many Mexico-based fentanyl cooks are having difficulty obtaining some key precursor chemicals,” the report noted. “DEA reporting indicates that some China-based chemical suppliers are wary of supplying controlled precursors to its international customers, demonstrating an awareness on their part that the government of China is controlling more fentanyl precursors to comply with recent updates to the United Nations counter-narcotics treaty.”
That doesn’t mean fentanyl is any safer.
“The downward trend in fentanyl purity does not mean that street-level fentanyl is less dangerous,” according to the report. “Drug dealers in the United States continue to adulterate fentanyl with various animal tranquilizers (such as xylazine), anesthetics (such as ketamine), and other synthetic opioids (such as nitazenes).”
DEA Acting Administrator Robert Murphy said the report shows progress.
“This year’s report indicates progress in the fight against fentanyl and also outlines the increasing challenges we face with the changing landscape of the synthetic drug crisis,” he said. “The adulterating of fentanyl with highly potent, dangerous chemicals reminds us that this fight is far from over.”
